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modafinil will lower the extent or result of pacritinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.Outcome of coadministration of a dual CYP3A4 and CYP2C19 inhibitor with fedratinib has not been examined.When the modafinil group had only the second ideal PVT scores and the worst Stanford Sleepiness Exam scores, they'd